Which statement about disulfiram-like interactions is supported by the material?

• A. Disulfiram-like reactions occur with several antibiotics but not Metronidazole
• B. Disulfiram-like reactions are unrelated to alcohol consumption
• C. Disulfiram-like reactions can occur with alcohol and Metronidazole
• D. No disulfiram-like reactions are noted with Metronidazole

Answer: (C)

Disulfiram-like reactions happen when certain drugs interact with alcohol, causing symptoms such as flushing, tachycardia, nausea, and vomiting due to an acetaldehyde buildup. Metronidazole is one of those drugs; when alcohol is consumed during or soon after taking metronidazole, these reactions can occur. So the statement that disulfiram-like reactions can occur with alcohol and Metronidazole is the supported one. The other options contradict this known interaction or ignore the role of alcohol in triggering the reaction.