When dispensing Accutane capsules to females of child-bearing age, which counseling point should be raised?

• A. Avoid pregnancy while using the drug
• B. Discontinue the drug if the acne gets worse
• C. Increase exposure to sunlight to help eliminate lesions
• D. All of the above

Answer: (A)

Isotretinoin is highly teratogenic, so the key counseling point for females of child‑bearing age is to avoid pregnancy during treatment and to use effective contraception as directed, with any required pregnancy testing. This focus on pregnancy prevention is what makes it the most important guidance. Discontinuing the drug if acne worsens isn’t an appropriate instruction to follow on your own; acne management should be guided by a clinician. Increasing sun exposure is not advised either, since isotretinoin increases photosensitivity and sun exposure won’t reliably improve lesions. So the essential message is to avoid pregnancy during therapy.